Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 7/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 4/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554937 | 1.00 | TDP1 (0.44) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| SCHEMBL28519747 | 1.00 | TDP1 (0.44) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526213 | 0.99 | TDP1 (0.43) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL21526212 | 0.99 | TDP1 (0.43) | TDP1ALDH1A1BACE1METAP2METAP1 | |
| SCHEMBL21554931 | 0.87 | CTSC (0.52) | TDP1ALDH1A1BACE1CTSDBACE2 | |
| SCHEMBL21526206 | 0.86 | ALDH1A1 (0.43) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21526205 | 0.86 | ALDH1A1 (0.43) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21012397 | 0.85 | SMN1; SMN2 (0.45) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL21555137 | 0.85 | SMN1; SMN2 (0.45) | TDP1ALDH1A1BACE1LTA4HCTSD | |
| SCHEMBL23921537 | 0.84 | LAP3 (0.46) | TDP1ALDH1A1BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788031-B1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED S L (ES) | 2023-09-27 | — | — | EP | disclosed |
| US-11242312-B2 | Dipeptidyl ketoamide meta-methoxyphenyl derivatives and uses thereof | LANDSTEINER GENMED, S.L. (ES) | 2022-02-08 | — | — | US | disclosed |
| US-20210317075-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2021-10-14 | — | — | US | disclosed |
| CN-112368263-A | Dipeptidyl ketoamide m-methoxyphenyl derivative and application thereof | 兰德施泰纳根梅德公司 | 2021-02-12 | — | — | CN | disclosed |
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242312-B2 | Dipeptidyl ketoamide meta-methoxyphenyl derivatives and uses thereof | DPP4, DPP7, DPP3 | TDP1 2806/4885ALDH1A1 1411/4885BACE1 463/4885 |
| US-20210317075-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | DPP4, DPP7, DPP3 | TDP1 2806/4885ALDH1A1 1411/4885BACE1 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.