Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28636303 | 0.95 | DPP3 (0.48) | DPP3OPRM1BCHECCKARCCKBR | |
| Trifluoroacetic Acid SCHEMBL18986061 | 0.95 | DPP3 (0.48) | DPP3OPRM1BCHECCKARCCKBR | |
| SCHEMBL19013087 | 0.88 | DPP4 (0.61) | DPP3BCHEDPP4 | |
| SCHEMBL29557726 | 0.86 | BCHE (0.55) | DPP3OPRM1BCHECCKARCCKBR | |
| Trifluoroacetic Acid SCHEMBL20575250 | 0.83 | DPP4 (0.55) | DPP3BCHEDPP4 | |
| Trifluoroacetic Acid SCHEMBL18985790 | 0.83 | DPP4 (0.55) | DPP3BCHEDPP4 | |
| SCHEMBL30478003 | 0.77 | DPP3 (0.52) | DPP3OPRM1BCHECCKARCCKBR | |
| SCHEMBL19012662 | 0.77 | HSD11B1 (0.45) | OPRM1DPP4OPRD1OPRK1 | |
| SCHEMBL30231933 | 0.77 | DPP3 (0.60) | DPP3OPRM1CCKARCCKBRTACR1 | |
| SCHEMBL15692330 | 0.76 | BCHE (0.63) | DPP3OPRM1BCHEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390359-B1 | (R)-N-(ADAMANTYL-2-YL)PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES FOR COSMETIC USE | DSM IP ASSETS BV (NL) | 2021-01-27 | — | — | EP | disclosed |
| US-10470991-B2 | (R)-N-(adamantyl-2-yl)pyrrolidine-2-carboxamide derivatives for cosmetic use | DSM IP ASSETS B.V. (NL) | 2019-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10470991-B2 | (R)-N-(adamantyl-2-yl)pyrrolidine-2-carboxamide derivatives for cosmetic use | HSD3B1, HSD11B1, HSD17B1 | DPP3 1114/4885OPRM1 3909/4885BCHE 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.