Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034634 | 0.76 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL8133096 | 0.76 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL20859102 | 0.76 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL8351646 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL30932632 | 0.74 | HTR2A (0.38) | P2RX7 | |
| Hydrochloric Acid SCHEMBL360922 | 0.74 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL17778049 | 0.73 | SAT1 (0.45) | P2RX7 | |
| SCHEMBL17776633 | 0.73 | SIGMAR1 (0.34) | — | |
| SCHEMBL22906 | 0.72 | APLNR (0.31) | — | |
| SCHEMBL1983555 | 0.72 | APLNR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221306-B1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |