Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL891608 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL31746086 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28539693 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4441601 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL8813383 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9551398 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL9551548 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL226551 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121736172-B | Composition for controlled release type ultrahigh temperature resistant salt resistant gel, preparation method and application thereof | 中国石油大学(北京) | 2026-05-19 | — | — | CN | claimed |
| CN-119391396-B | Oil-free phase resistance reducing agent for fracturing fluid and preparation method thereof | 中石化石油工程技术服务股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122011276-A | Oil reservoir deep profile control and flooding combined particle, and preparation method and application thereof | 中海石油（中国）有限公司天津分公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260042710-A1 | METHOD FOR PRODUCING ZIRCONIA POWDER CONTAINING MULTIPLE RARE EARTH ELEMENTS | NAT CHUNG SHAN INST SCIENCE & TECH (TW) | 2026-02-12 | — | — | US | claimed |
| US-12371444-B2 | Methods of making MOFs, systems for synthesizing MOFs, and methods of coating textiles with MOFs | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-07-29 | — | — | US | claimed |
| CN-119368161-B | Core-shell structure three-way catalyst for reducing automobile exhaust emission and preparation method thereof | 东华大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119455920-B | Dual-functional fluorescent probe adsorption material and preparation method and application thereof | 合肥科环环境科技股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119909740-A | Multilayer core-shell structure catalyst, preparation method and application thereof in synthesizing 1, 3-propylene glycol from glycerol | 中国石油化工股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119912932-A | Fracturing fluid system for compact limestone, preparation method and application thereof | 中国石油天然气股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119542484-B | Slurry type manganese positive electrode electrolyte for flow battery | 浙江师范大学 | 2025-04-18 | — | — | CN | claimed |
| WO-1997022638-A1 | COMPOSITIONS AND PROCESSES FOR TREATING SUBTERRANEAN FORMATIONS | PHILLIPS PETROLEUM COMPANY (US) | 1997-06-26 | — | — | WO | claimed |
| US-5614475-A | CROSSLINKED WITH ZIRCONIUM, VISCOSITY STABILTY AT HIGH TEMPERATURE | RHONE-POULENC INC. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1996034179-A1 | CARBOXYALKYL SUBSTITUTED POLYGALACTOMANNAN FRACTURING FLUIDS | RHONE-POULENC INC. (US) | 1996-10-31 | — | — | WO | claimed |
| US-5547025-A | INJECTING A GELLING COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1996-08-20 | — | — | US | claimed |
| EP-0668432-A2 | Process for treating oil-bearing formation | PHILLIPS PETROLEUM COMPANY (US) | 1995-08-23 | — | — | EP | claimed |
| US-5423380-A | Adding crosslinking agent intermittently to stream of aqueous solution of gellable polymer injected into subterranean formation | PHILLIPS PETROLEUM COMPANY (US) | 1995-06-13 | — | — | US | claimed |
| EP-0549156-A1 | Process for oligomerizing olefins using titanium salts or zirconium salts deposited on silicon dioxide | TEXACO CHEMICAL COMPANY (US) | 1993-06-30 | — | — | EP | claimed |
| EP-0524733-A1 | Process for oligomerizing olefins using halogen-free titanium salts or halogen-free zirconium salts on clays | TEXACO CHEMICAL COMPANY (US) | 1993-01-27 | — | — | EP | claimed |
| US-5146030-A | Synthetic lubricants | TEXACO CHEMICAL COMPANY (US) | 1992-09-08 | — | — | US | claimed |
| US-3966502-A | Zirconium rinse for phosphate coated metal surfaces | AMCHEM PRODUCTS, INC. (US) | 1976-06-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042710-A1 | METHOD FOR PRODUCING ZIRCONIA POWDER CONTAINING MULTIPLE RARE EARTH ELEMENTS | ZRANB2, SON, PIEZO1 | CA4 95/4885ALDH1A1 4803/4885CASP1 2732/4885 |
| US-12371444-B2 | Methods of making MOFs, systems for synthesizing MOFs, and methods of coating textiles with MOFs | PIEZO1, CUTA, MASTL | CA4 31/4885ALDH1A1 2709/4885CASP1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.