Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477436 | 0.85 | TLR8 (0.40) | TLR8TLR7ALDH1A1CCNA2CDK2 | |
| SCHEMBL8664924 | 0.85 | CCNA2 (0.35) | TLR8TLR7ALDH1A1CCNA2CDK2 | |
| SCHEMBL30593321 | 0.78 | TLR8 (0.48) | TLR8TLR7ALDH1A1CYP2C19 | |
| SCHEMBL24567768 | 0.78 | TLR8 (0.48) | TLR8TLR7ALDH1A1CYP2C19 | |
| SCHEMBL9272660 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CYP2C19 | |
| SCHEMBL20032032 | 0.72 | MAPT (0.47) | TLR8TLR7ALDH1A1CYP2C19LMNA | |
| SCHEMBL1268977 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CCNA2CDK2CCNA1CDK5 | |
| SCHEMBL20852463 | 0.71 | CYP1A2 (0.45) | ALDH1A1CYP2C19LMNAHTT | |
| SCHEMBL20852553 | 0.71 | FDPS (0.44) | TLR8TLR7ALDH1A1CYP2C19 | |
| SCHEMBL20852582 | 0.71 | FFAR2 (0.34) | TLR8TLR7TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |