Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20852549 | 0.83 | HIF1A (0.61) | BCAT2HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL14769097 | 0.83 | HIF1A (0.61) | BCAT2HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL19361242 | 0.81 | BCAT2 (0.45) | BCAT2HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL18401333 | 0.81 | BCAT2 (0.45) | BCAT2HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL13840699 | 0.81 | BCAT2 (0.45) | BCAT2HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL18884493 | 0.80 | AOC3 (0.61) | HIF1AHDAC4HDAC7HDAC5ADRB2 | |
| SCHEMBL14769096 | 0.80 | BCAT2 (0.68) | BCAT2RAB9AAOC3LMNAKDM4E | |
| SCHEMBL3921879 | 0.80 | BCAT2 (0.68) | BCAT2RAB9AAOC3LMNAKDM4E | |
| SCHEMBL4440959 | 0.79 | BCAT2 (0.50) | BCAT2HDAC4HDAC7HDAC5ADRB1 | |
| SCHEMBL21556957 | 0.78 | ADRB2 (0.42) | HIF1AADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |