Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1429521 | 0.83 | HDAC4 (0.45) | BCAT2NPC1RAB9AHDAC4HDAC7 | |
| SCHEMBL1231342 | 0.83 | GBA1 (0.51) | HDAC4HDAC7HDAC5CNR2CES2 | |
| SCHEMBL1520684 | 0.81 | BCAT2 (0.72) | BCAT2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL26906281 | 0.81 | BCAT2 (0.72) | BCAT2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4596502 | 0.81 | ADRB3 (0.53) | BCAT2ADRB1ADRB3 | |
| SCHEMBL4437771 | 0.80 | PNMT (0.59) | BCAT2NPC1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL4440894 | 0.80 | PNMT (0.59) | BCAT2NPC1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL20430458 | 0.80 | BCAT2 (0.51) | BCAT2NPC1RAB9AHDAC4HDAC7 | |
| SCHEMBL5751931 | 0.80 | BCAT2 (0.51) | BCAT2NPC1RAB9AHDAC4HDAC7 | |
| SCHEMBL21556958 | 0.79 | BCAT2 (0.45) | BCAT2RAB9AHDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |