Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445887 | 0.86 | MAPT (0.60) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL13840703 | 0.82 | MAPT (0.47) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL14769308 | 0.82 | MAPT (0.44) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL19361259 | 0.82 | ADRB1 (0.63) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL21556952 | 0.79 | ADRB1 (0.42) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL21556906 | 0.79 | BCAT2 (0.46) | TDP1KDM4EALDH1A1HIF1ABLM | |
| SCHEMBL289129 | 0.78 | KDM4E (0.72) | MAPTTDP1ADRB2ADRB1KDM4E | |
| SCHEMBL19361242 | 0.77 | BCAT2 (0.45) | ADRB2ADRB1KDM4EADRB3TSHR | |
| SCHEMBL22826941 | 0.76 | ADRA2A (0.41) | TDP1ADRB2ADRB1KDM4EADRB3 | |
| SCHEMBL14769097 | 0.75 | HIF1A (0.61) | ADRB2ADRB1KDM4EADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |