Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833268 | 0.87 | ASIC3 (0.49) | HTR1AHTR7SYKASIC3 | |
| SCHEMBL1010747 | 0.87 | ASIC3 (0.56) | HTR1AHTR7SYKPIM1PIM3 | |
| SCHEMBL1011236 | 0.87 | ASIC3 (0.49) | HTR1AHTR7SYKASIC3 | |
| SCHEMBL31070452 | 0.81 | KDM4E (0.39) | HTR1AHTR7SYKKDM4ELMNA | |
| SCHEMBL23351094 | 0.77 | CYP11B1 (0.47) | HTR1AHTR7KDM4ELMNACYP1A2 | |
| SCHEMBL4024459 | 0.77 | CYP11B1 (0.51) | HTR1AHTR7KDM4ELMNACYP1A2 | |
| SCHEMBL4025451 | 0.76 | CYP11B1 (0.50) | HTR1AHTR7KDM4ELMNACYP1A2 | |
| SCHEMBL21557592 | 0.75 | PDK2 (0.40) | HTR1AHTR7KDM4ELMNACYP1A2 | |
| SCHEMBL6130756 | 0.75 | PDK2 (0.51) | HTR1AHTR7KDM4ELMNACYP1A2 | |
| SCHEMBL20599454 | 0.74 | NTRK2 (0.65) | PDK2CYP2A6PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |