SCHEMBL4025451

SCHEMBL4025451

[Ir].c1ccc(-c2ccc3c(c2)CCCC3)nc1.c1ccc(-c2ccc3c(c2)CCCC3)nc1.c1ccc(-c2ccc3c(c2)CCCC3)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.50
CYP11B2 P19099 1/20 0.50
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
RAB9A P51151 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 3/20 0.43
LMNA P02545 2/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CCR1 P32246 1/20 0.43
CCR5 P51681 1/20 0.43
CCR8 P51685 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4024459 0.98 CYP11B1 (0.51) CYP11B1CYP11B2MEN1MAPTKMT2A
SCHEMBL23351094 0.95 CYP11B1 (0.47) CYP11B1CYP11B2MEN1MAPTKMT2A
SCHEMBL8024916 0.79 MAOA (0.53) KCNH2
SCHEMBL30833268 0.78 ASIC3 (0.49) HTR1AHTR7
SCHEMBL1010747 0.78 ASIC3 (0.56) HTR1AHTR7
SCHEMBL5713849 0.78 PDK2 (0.42) SMN1; SMN2TP53ALOX15KDM4ELMNA
SCHEMBL1011236 0.78 ASIC3 (0.49) HTR1AHTR7
SCHEMBL30641498 0.76 MAOA (0.49) PDK2CNR2NPY5RCYP2A6CREBBP
SCHEMBL5713852 0.76 PDK2 (0.38) MAPTSMN1; SMN2ALDH1A1TP53ALOX15
SCHEMBL21810824 0.76 RIPK1 (0.56) MAPTSMN1; SMN2NPC1TP53RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598879-B1 LUMINESCENCE DEVICE, DISPLAY APPARATUS AND METAL COORDINATION COMPOUND CANON KK (JP) 2015-12-02 EP disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7026062-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-04-11 US disclosed
EP-1191613-B1 Luminescence device, display apparatus and metal coordination compound CANON KK (JP) 2006-03-29 EP disclosed
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1598879-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-11-23 EP disclosed
US-20050014025-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-01-20 US disclosed
US-6815091-B2 IRIDIUM, RHODIUM, OR PALLADIUM-PHENYLPYRIDINE COMPLEX WITH SPECIFIED SUBSTITUENT(S); HIGH-EFFICIENCY LUMINESCENCE, HIGH BRIGHTNESS FOR A LONG TIME WHILE MINIMIZING DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-09 US disclosed
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191613-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound SOD1, ICOSLG, CCRL2 CYP11B1 3018/4885CYP11B2 2617/4885MEN1 1695/4885
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CDYL, ZC3HAV1L, ICOSLG CYP11B1 1770/4885CYP11B2 1463/4885MEN1 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.