SCHEMBL4024459

SCHEMBL4024459

c1ccc(-c2ccc3c(c2)CCCC3)nc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.49
TP53 P04637 3/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
ALOX15 P16050 2/20 0.49
NPC1 O15118 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
RAB9A P51151 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 4/20 0.45
LMNA P02545 3/20 0.45
CCR1 P32246 2/20 0.45
CCR5 P51681 2/20 0.45
CCR8 P51685 2/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4025451 0.98 CYP11B1 (0.50) CYP11B1CYP11B2SMN1; SMN2TP53MEN1
SCHEMBL23351094 0.96 CYP11B1 (0.47) CYP11B1CYP11B2SMN1; SMN2TP53MEN1
SCHEMBL8024916 0.80 MAOA (0.53)
SCHEMBL30833268 0.79 ASIC3 (0.49) HTR1AHTR7
SCHEMBL1010747 0.79 ASIC3 (0.56) HTR1AHTR7
SCHEMBL5713849 0.79 PDK2 (0.42) SMN1; SMN2TP53ALOX15KDM4ELMNA
SCHEMBL1011236 0.79 ASIC3 (0.49) HTR1AHTR7
SCHEMBL21810824 0.78 RIPK1 (0.56) SMN1; SMN2TP53MAPTNPC1RAB9A
SCHEMBL30641498 0.78 MAOA (0.49) PDK2CNR2NPY5RCYP2A6
SCHEMBL8025414 0.78 MAOA (0.50) METAP1HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598879-B1 LUMINESCENCE DEVICE, DISPLAY APPARATUS AND METAL COORDINATION COMPOUND CANON KK (JP) 2015-12-02 EP disclosed
US-20110212956-A1 Pyrazolopyrimidines for treating CNS disorders MERZ PHARMA GMBH & CO. KGAA (DE) 2011-09-01 US disclosed
EP-1489111-B1 POLYMERIC COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KK (JP) 2010-12-29 EP disclosed
US-7691493-B2 Polymeric compound and organic luminescence device CANON KABUSHIKI KAISHA (JP) 2010-04-06 US disclosed
US-7691493-B2 Polymeric compound and organic luminescence device CANON KABUSHIKI KAISHA (JP) 2010-04-06 US disclosed
US-20090230860-A1 POLYMER COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KABUSHIKI KAISHA (JP) 2009-09-17 US disclosed
US-20090230860-A1 POLYMER COMPOUND AND ELECTROLUMINESCENT ELEMENT CANON KABUSHIKI KAISHA (JP) 2009-09-17 US disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7534506-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-7238435-B2 Polymeric compound and organic luminescence device CANON KABUSHIKI KAISHA (JP) 2007-07-03 US disclosed
US-7238435-B2 Polymeric compound and organic luminescence device CANON KABUSHIKI KAISHA (JP) 2007-07-03 US disclosed
US-7026062-B2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-04-11 US disclosed
EP-1191613-B1 Luminescence device, display apparatus and metal coordination compound CANON KK (JP) 2006-03-29 EP disclosed
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1598879-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-11-23 EP disclosed
US-20050014025-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-01-20 US disclosed
US-6815091-B2 IRIDIUM, RHODIUM, OR PALLADIUM-PHENYLPYRIDINE COMPLEX WITH SPECIFIED SUBSTITUENT(S); HIGH-EFFICIENCY LUMINESCENCE, HIGH BRIGHTNESS FOR A LONG TIME WHILE MINIMIZING DETERIORATION IN LUMINESCENCE IN ENERGIZED STATE CANON KABUSHIKI KAISHA (JP) 2004-11-09 US disclosed
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1191613-A2 Luminescence device, display apparatus and metal coordination compound CANON KABUSHIKI KAISHA (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212956-A1 Pyrazolopyrimidines for treating CNS disorders GRM5, GRM3, GRM1 CYP11B1 407/4885CYP11B2 305/4885SMN1; SMN2 897/4885
US-20060014047-A1 Luminescence device, display apparatus and metal coordination compound SOD1, ICOSLG, CCRL2 CYP11B1 3018/4885CYP11B2 2617/4885SMN1; SMN2 1992/4885
US-20020064681-A1 Luminescence device, display apparatus and metal coordination compound CDYL, ZC3HAV1L, ICOSLG CYP11B1 1770/4885CYP11B2 1463/4885SMN1; SMN2 2984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.