SCHEMBL21559906

SCHEMBL21559906

CNC(CCNC(=N)N)C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPY4R P50391 3/20 0.30
NPY1R P25929 2/20 0.30
NPY2R P49146 2/20 0.30
NPY5R Q15761 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11950333 0.89 NPY4R (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL8227032 0.89 NPY4R (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL14028975 0.89 NPY4R (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL19487472 0.88 ALOX15 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL18356744 0.88 ALOX15 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL30208240 0.85 TGFBR1 (0.32) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL19487357 0.85 KISS1R (0.31)
SCHEMBL26466762 0.82 ANPEP (0.30) ALOX15
SCHEMBL26546113 0.82 ALOX15 (0.30) ALOX15
SCHEMBL14942945 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 ALOX15 760/4885MEN1 3408/4885CYP1A2 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.