Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549124 | 0.76 | TP53 (0.39) | TP53 | |
| SCHEMBL28837325 | 0.74 | CFTR (0.33) | CFTR | |
| SCHEMBL28811327 | 0.74 | CFTR (0.33) | CFTR | |
| SCHEMBL28811326 | 0.74 | CFTR (0.33) | CFTR | |
| SCHEMBL4410073 | 0.73 | — | — | |
| SCHEMBL27360028 | 0.73 | — | — | |
| SCHEMBL1133057 | 0.73 | — | — | |
| SCHEMBL3160885 | 0.73 | — | — | |
| SCHEMBL13771507 | 0.72 | CFTR (0.31) | CFTR | |
| SCHEMBL7054792 | 0.72 | TP53 (0.35) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633341-B2 | Picolinic acid derivatives and their use as intermediates | NOVARTIS AG (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20190345107-A1 | NEW PICOLINIC ACID DERIVATIVES AND THEIR USE AS INTERMEDIATES | NOVARTIS AG (CH) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345107-A1 | NEW PICOLINIC ACID DERIVATIVES AND THEIR USE AS INTERMEDIATES | PYCR1, HADHA, HPD | TP53 4385/4885CFTR 649/4885 |
| US-10633341-B2 | Picolinic acid derivatives and their use as intermediates | HPD, PYCR1, PAH | TP53 4437/4885CFTR 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.