SCHEMBL21563548

SCHEMBL21563548

Cc1cc(C)c(C(C)c2cc(C)ccc2/N=C2C(=N/c3ccc(C)cc3C(C)c3c(C)cc(C)cc3C)/c3cccc4cccc/2c34)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CASR P41180 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563550 0.81 KDM4E (0.33) LMNAGAAALDH1A1
SCHEMBL12445130 0.71 ALDH1A1 (0.46) LMNAGAAALDH1A1MEN1KMT2A
SCHEMBL21114848 0.71 MEN1 (0.50) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL12304879 0.71 MEN1 (0.50) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL19625540 0.70 MEN1 (0.42) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL7102309 0.70 MEN1 (0.49) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL29621536 0.69 ALDH1A1 (0.35) ALDH1A1MEN1KMT2A
Bromide SCHEMBL6247031 0.68 MEN1 (0.48) LMNAALDH1A1MEN1KMT2ACYP1A2
SCHEMBL22708327 0.65
SCHEMBL31387955 0.65 ALDH1A1 (0.36) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230117728-A1 LIGHT AS CATALYTIC SWITCH: METAL-ORGANIC INSERTION/LIGHT INITIATED RADICAL (MILRad) POLYMERIZATION UNIVERSITY OF HOUSTON SYSTEM (US) 2023-04-20 US disclosed
WO-2019217930-A1 LIGHT AS CATALYTIC SWITCH: METAL-ORGANIC INSERTION/LIGHT INITIATED RADICAL (MILRad) POLYMERIZATION UNIVERSITY OF HOUSTON SYSTEM (US) 2019-11-14 WO disclosed