Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230200 | 0.82 | MEN1 (0.51) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL2230195 | 0.82 | MEN1 (0.51) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL2231358 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL2231354 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL3804212 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL3804209 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL14367153 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL21563548 | 0.71 | LMNA (0.33) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL14393077 | 0.70 | ALDH1A1 (0.64) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL14367152 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CES2BCHECES1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977269-B2 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-12 | — | — | US | disclosed |
| US-7977269-B2 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-12 | — | — | US | disclosed |
| US-20100222577-A1 | Diimine Metal Complexes, Methods of Synthesis, and Methods of Using in Oligomerization and Polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222577-A1 | Diimine Metal Complexes, Methods of Synthesis, and Methods of Using in Oligomerization and Polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-09-02 | — | — | US | disclosed |
| US-7727926-B2 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-06-01 | — | — | US | disclosed |
| US-7727926-B2 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070112150-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2007-05-17 | — | — | US | disclosed |
| US-20070112150-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222577-A1 | Diimine Metal Complexes, Methods of Synthesis, and Methods of Using in Oligomerization and Polymerization | PICALM, SPR, AP2M1 | ALDH1A1 2596/4885CES2 4563/4885BCHE 4782/4885 |
| US-20070112150-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | PICALM, SPR, AP2M1 | ALDH1A1 2609/4885CES2 4622/4885BCHE 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.