Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565688 | 0.89 | CLK4 (0.49) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL18650958 | 0.80 | CLK4 (0.58) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL10187283 | 0.77 | ADORA2A (0.57) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL15533860 | 0.77 | CLK4 (0.57) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL19596599 | 0.73 | CLK4 (0.51) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL17788472 | 0.73 | NPC1 (0.60) | LMNATP53SMN1; SMN2HPGDNPC1 | |
| SCHEMBL14741834 | 0.72 | KMO (0.57) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL20380088 | 0.72 | KDM4E (0.59) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30501033 | 0.72 | KDM4E (0.59) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL21565691 | 0.71 | CLK4 (0.50) | CLK4ALDH1A1HSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015793-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | ETH ZURICH (CH) | 2021-01-21 | — | — | US | disclosed |
| US-20190343802-A1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | ETH Zürich (CH) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190343802-A1 | CELL-PROTECTIVE COMPOUNDS AND THEIR USE | SRPK2, SRSF2, SRPK1 | CLK4 1774/4885ALDH1A1 3877/4885HSD17B10 1904/4885 |
| US-20210015793-A1 | COMPOUNDS FOR TREATING CNS- AND NEURODEGENERATIVE DISEASES | PPT1, SPTLC1, LPCAT1 | CLK4 3816/4885ALDH1A1 712/4885HSD17B10 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.