Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.79 |
| ▸ | MEN1 | O00255 | 6/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | ATM | Q13315 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ACP1 | P24666 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568038 | 0.88 | KMT2A (1.00) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL27093077 | 0.87 | DYRK1A (0.67) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL23256372 | 0.85 | KMT2A (0.73) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL4919955 | 0.82 | KDM4E (1.00) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL21858356 | 0.82 | CXCR2 (0.69) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL31206289 | 0.82 | CXCR2 (0.69) | KMT2AMEN1ALDH1A1POLBLMNA | |
| SCHEMBL6463656 | 0.80 | ALDH1A1 (0.71) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL4124786 | 0.79 | DYRK1A (0.74) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL27093090 | 0.79 | NPC1 (0.80) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL27093078 | 0.79 | KDR (0.75) | KMT2AMEN1KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |