Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23256896 | 0.84 | DYRK1A (0.58) | DYRK1ADYRK1BABL1PIK3CGMAPT | |
| SCHEMBL27093077 | 0.80 | DYRK1A (0.67) | DYRK1ADYRK1BMAPTMEN1KMT2A | |
| SCHEMBL21568117 | 0.79 | DYRK1A (0.60) | DYRK1ADYRK1BMAPTMEN1KMT2A | |
| SCHEMBL6067759 | 0.79 | ABL1 (0.72) | DYRK1ADYRK1BABL1PIK3CGMAPT | |
| SCHEMBL21568317 | 0.78 | PIK3CA (0.60) | DYRK1ADYRK1BPIK3CGMAPTMEN1 | |
| SCHEMBL4124786 | 0.77 | DYRK1A (0.74) | DYRK1ADYRK1BMAPTMEN1KMT2A | |
| SCHEMBL6068042 | 0.76 | ABL1 (0.82) | DYRK1ADYRK1BABL1PIK3CGMAPT | |
| SCHEMBL27093078 | 0.76 | KDR (0.75) | DYRK1ADYRK1BMAPTMEN1KMT2A | |
| SCHEMBL8290119 | 0.76 | DYRK1A (0.62) | DYRK1ADYRK1BMAPTMEN1KMT2A | |
| SCHEMBL1651394 | 0.76 | PIK3CG (0.79) | DYRK1AABL1PIK3CGMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |