Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568288 | 0.87 | DYRK1A (0.55) | DYRK1APIK3CGABL1GSK3BPDPK1 | |
| SCHEMBL23256896 | 0.77 | DYRK1A (0.58) | DYRK1APIK3CGABL1GSK3B | |
| SCHEMBL21568046 | 0.75 | GSK3B (0.65) | DYRK1AWNT3AABL1GSK3BRIPK1 | |
| SCHEMBL23256882 | 0.74 | DYRK1A (0.58) | DYRK1AADORA2AADORA1PDPK1 | |
| SCHEMBL13718453 | 0.73 | DYRK1A (0.74) | DYRK1APIK3CGABL1GSK3BCSNK1D | |
| SCHEMBL23256883 | 0.73 | DYRK1A (0.66) | DYRK1AGSK3BCSNK1D | |
| SCHEMBL21569113 | 0.72 | CSNK1D (0.54) | DYRK1AMGLLCSNK1D | |
| SCHEMBL23256870 | 0.72 | DYRK1A (0.70) | DYRK1AGSK3BCSNK1D | |
| SCHEMBL21568692 | 0.70 | DYRK1A (1.00) | DYRK1APIK3CGGSK3BADORA1CSNK1D | |
| SCHEMBL6067966 | 0.70 | DYRK1A (0.76) | DYRK1APIK3CGABL1GSK3BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217509-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | HB THERAPEUTICS INC. (US) | 2019-11-14 | — | — | WO | disclosed |