SCHEMBL2157002

SCHEMBL2157002

Cc1ccc(C(=O)C(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 12/20 1.00
CES1 P23141 11/20 1.00
RAB9A P51151 3/20 0.65
NPC1 O15118 2/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
ALDH1A1 P00352 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 2/20 0.59
POLB P06746 1/20 0.59
AKR1C3 P42330 1/20 0.55
MAPT P10636 1/20 0.55
SRD5A2 P31213 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL9504586 0.92 CES2 (0.86) CES2CES1RAB9ANPC1MEN1
SCHEMBL167254 0.89 CES2 (1.00) CES2CES1RAB9ANPC1MEN1
Benzil SCHEMBL4957522 0.87 CES2 (1.00) CES2CES1RAB9AALDH1A1SRD5A2
SCHEMBL1195835 0.87 CES2 (1.00) CES2CES1RAB9AALDH1A1SRD5A2
SCHEMBL259065 0.85 ALDH1A1 (0.80) CES2CES1RAB9ANPC1MEN1
4-Methylbenzoic Acid SCHEMBL14723409 0.85 ALDH1A1 (0.85) CES2CES1RAB9ANPC1MEN1
Benzophenone SCHEMBL5162782 0.85 ALDH1A1 (0.80) CES2CES1RAB9ANPC1MEN1
4-Methylbenzoic Acid SCHEMBL7940172 0.85 ALDH1A1 (0.85) CES2CES1RAB9ANPC1MEN1
SCHEMBL235 0.85 ALDH1A1 (0.80) CES2CES1RAB9ANPC1MEN1
Benzil SCHEMBL27849222 0.85 CES2 (0.74) CES2CES1RAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7973034-B2 Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2011-07-05 US claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
CN-114410043-B Sealing member for semiconductor device and method for manufacturing the same 有谛工业科技(上海)有限公司 2023-08-15 CN disclosed
CN-113755862-B Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2022-08-19 CN disclosed
CN-114410043-A Sealing member for semiconductor device and method for manufacturing the same 有谛工业科技(上海)有限公司 2022-04-29 CN disclosed
CN-113755862-A Method for preparing aromatic alpha-diketone compound by electrochemical oxidation 西南大学 2021-12-07 CN disclosed
CN-107935803-B Synthetic method of 1, 2-diketone compound 浙江工业大学 2020-11-13 CN disclosed
EP-2738611-B1 Positively chargeable monolayer electrophotographic photosensitive member and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC (JP) 2018-03-28 EP disclosed
US-9541849-B2 Positively chargeable single-layer electrophotographic photosensitive member and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-01-10 US disclosed
US-9293713-B2 Arylamine compound RICOH COMPANY, LTD. (JP) 2016-03-22 US disclosed
EP-1403710-B1 Polymerizable composition FUJIFILM CORP (JP) 2015-06-10 EP disclosed
US-5071870-A Methyl carbamate assistant; controlling vapor pressure; high f lesh point; clothing MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1991-12-10 US disclosed
US-4967010-A IN APROTIC SOLVENT IN PRESENCE OF UREA DERIVATIVE BASF AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
EP-0362638-A2 Method of preparing symmetrical and unsymmetrical monoacetals of aromatic 1,2-diketones BASF Aktiengesellschaft (DE) 1990-04-11 EP disclosed
EP-0100862-B1 2-ACYL-DIHYDRO-1,3-DIOXEPINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHOTOINITIATORS CIBA-GEIGY AG (CH) 1987-08-19 EP disclosed
US-4485249-A 2-Acylated dihydro-1,3-dioxepins, process for the production thereof and use thereof as photo-initiators CIBA-GEIGY CORPORATION (US) 1984-11-27 US disclosed
EP-0100862-A1 2-Acyl-dihydro-1,3-dioxepines, process for their preparation and their use as photoinitiators CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
US-4287367-A Manufacture of symmetrical or unsymmetrical monoacetals of aromatic 1,2-diketones BASF AKTIENGESELLSCHAFT (DE) 1981-09-01 US disclosed
US-4190602-A PHOTOCHEMICAL SENSITIZERS BY REACTION OF SULFUROUS ACID ESTER OR THIONYL CHLORIDE AND A PRIMARY ALCOHOL CIBA-GEIGY CORPORATION (US) 1980-02-26 US disclosed
US-4144156-A Manufacture of unsymmetric monoacetals of aromatic 1,2-diketones employable as photoiniatiators BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed