Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 9/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 7/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570663 | 0.85 | HTT (0.35) | ACACAEPHX2POLBHTTNPSR1 | |
| SCHEMBL21570630 | 0.84 | ACACA (0.37) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL21570639 | 0.82 | ACACA (0.43) | ACACAEPHX2POLBHTTNPSR1 | |
| SCHEMBL29581152 | 0.81 | ACACA (0.42) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL22870047 | 0.81 | ACACA (0.42) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL22869915 | 0.81 | ACACA (0.42) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL28683936 | 0.81 | ACACA (0.42) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL21570681 | 0.77 | ACACA (0.43) | ACACAPOLBHTTNPSR1L3MBTL1 | |
| SCHEMBL21570700 | 0.76 | EPHX2 (0.38) | ACACAEPHX2POLBHTTNPSR1 | |
| SCHEMBL21570598 | 0.75 | ACACA (0.45) | ACACAPOLBHTTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3571205-B1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-09-01 | — | — | US | disclosed |
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190352311-A1 | THIENOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | ACACA, ACACB, PC | ACACA 1/4885EPHX2 621/4885POLB 1001/4885 |
| US-10759812-B2 | Thienopyrimidine derivative and use thereof in medicine | ACACA, ACACB, PC | ACACA 1/4885EPHX2 621/4885POLB 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.