Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 5/20 | 0.38 |
| ▸ | FNTB | P49356 | 5/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | LDLR | P01130 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474189 | 0.72 | ALDH1A1 (0.50) | MAOA | |
| SCHEMBL21075974 | 0.71 | RORC (0.47) | RORC | |
| SCHEMBL21538814 | 0.70 | PSMB5 (0.36) | TLR7CLK1 | |
| SCHEMBL18754515 | 0.70 | FNTA (0.53) | RORCFNTAFNTBPGGT1B | |
| SCHEMBL20474245 | 0.69 | PRNP (0.45) | ATM | |
| SCHEMBL28176611 | 0.68 | PSMB5 (0.51) | — | |
| SCHEMBL11166756 | 0.68 | TLR7 (0.51) | TLR7 | |
| SCHEMBL20799508 | 0.67 | KDM4E (0.50) | — | |
| SCHEMBL18754776 | 0.66 | RORC (0.38) | RORCFNTAFNTBLDLRPCSK9 | |
| SCHEMBL16632803 | 0.65 | RORC (0.59) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057421-B1 | ALKYL LINKED QUINOLINYL MODULATORS OF ROR(GAMMA)T | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-20 | — | — | EP | disclosed |