Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
| ▸ | FEN1 | P39748 | 3/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.34 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.34 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.34 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.34 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.34 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.34 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.34 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15951410 | 0.89 | NNMT (0.59) | NNMTMBGRM5ASIC3DRD2 | |
| SCHEMBL8385272 | 0.80 | NNMT (0.53) | NNMTGRM5ASIC3DRD2DRD4 | |
| SCHEMBL10283350 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL1723715 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL13538508 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL828125 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL13154323 | 0.76 | NNMT (0.57) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL13004722 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL298258 | 0.76 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL13332912 | 0.76 | NNMT (0.53) | NNMTMBGRM5ASIC3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569588-A1 | PROCESS FOR PREPARING A SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF AN APOPTOSIS-INDUCING AGENT | AbbVie Inc. (US) | 2019-11-20 | — | — | EP | disclosed |