Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20688772 | 0.92 | CTSD (0.44) | CTSDCTSLCTSBCTSSNPSR1 | |
| SCHEMBL16932535 | 0.86 | NPSR1 (0.42) | CTSDCTSLCTSBCTSSNPSR1 | |
| SCHEMBL2376936 | 0.86 | CTSD (0.46) | CTSDCTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL16932537 | 0.82 | PAOX (0.51) | CTSDCTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL16932531 | 0.82 | PAOX (0.51) | CTSDCTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL76415 | 0.79 | HRH3 (0.45) | CTSDCTSLCTSBCTSSNPSR1 | |
| SCHEMBL7783463 | 0.79 | HDAC6 (0.38) | MEN1KMT2A | |
| SCHEMBL7334634 | 0.77 | SMN1; SMN2 (0.51) | CTSDCTSLCTSBCTSSSMN1; SMN2 | |
| SCHEMBL1033434 | 0.77 | KEAP1 (0.54) | NPSR1SMN1; SMN2USP2ALDH1A1LMNA | |
| SCHEMBL9358875 | 0.77 | POLB (0.47) | SMN1; SMN2ALDH1A1LMNAKMT2ACD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099691-B1 | PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS | PROMEGA CORP (US) | 2019-11-20 | — | — | EP | disclosed |