Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853346 | 0.82 | PPARG (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17838856 | 0.81 | PPARG (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL21575105 | 0.80 | TACR1 (0.42) | SLC6A2SLC6A4SLC6A3TACR1MEN1 | |
| SCHEMBL548295 | 0.75 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3TACR1MEN1 | |
| SCHEMBL17853443 | 0.74 | CA2 (0.44) | SLC6A2SLC6A4SLC6A3TACR1CHIT1 | |
| Hydrochloric Acid SCHEMBL17838889 | 0.73 | CA2 (0.43) | SLC6A2SLC6A4SLC6A3TACR1CHIT1 | |
| SCHEMBL16097011 | 0.69 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3TACR1MEN1 | |
| SCHEMBL16825796 | 0.68 | CHIA (0.53) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL17838827 | 0.67 | KMT2A (0.47) | MEN1KMT2AALDH1A1CHIT1CHIA | |
| SCHEMBL5583514 | 0.66 | ABCB11 (0.48) | SLC6A2SLC6A4SLC6A3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |