Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476376 | 0.78 | MEN1 (0.67) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL18301172 | 0.78 | PIP4K2A (1.00) | PIP4K2AKMT2AMEN1NPC1CLK2 | |
| SCHEMBL18301135 | 0.78 | PIP4K2A (1.00) | PIP4K2AKMT2AMEN1NPC1CLK2 | |
| SCHEMBL18301104 | 0.78 | PIP4K2A (0.67) | MAPTKDM4EPIP4K2AKMT2AMEN1 | |
| SCHEMBL18301103 | 0.78 | PIP4K2A (0.67) | MAPTKDM4EPIP4K2AKMT2AMEN1 | |
| SCHEMBL5594404 | 0.75 | APP (0.64) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL27983608 | 0.74 | MAPT (0.82) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL5594463 | 0.73 | MEN1 (0.67) | MAPTKDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL20293921 | 0.72 | PIP4K2A (0.74) | PIP4K2AKMT2AMEN1NPC1CHEK1 | |
| SCHEMBL20293915 | 0.72 | PIP4K2A (0.74) | MAPTPIP4K2AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190350964-A1 | ANTI-CANCER COMPOUNDS AND USES THEREOF | NAT UNIV SINGAPORE (SG) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190350964-A1 | ANTI-CANCER COMPOUNDS AND USES THEREOF | PIK3CD, PIK3CA, PI4KB | MAPT 4442/4885KDM4E 1696/4885PIP4K2A 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.