Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KIF20A | O95235 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476376 | 0.82 | MEN1 (0.67) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL27983608 | 0.81 | MAPT (0.82) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL4328855 | 0.79 | APP (1.00) | APPMAPTKDM4EMEN1KMT2A | |
| SCHEMBL11657765 | 0.78 | KIF20A (0.71) | APPMAPTKDM4EMEN1KMT2A | |
| SCHEMBL10476384 | 0.78 | THRB (0.79) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL5594463 | 0.78 | MEN1 (0.67) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL10476377 | 0.77 | MEN1 (0.60) | APPMAPTKDM4EMEN1KMT2A | |
| SCHEMBL12351215 | 0.77 | MAPT (0.65) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL21578429 | 0.75 | MAPT (0.64) | MAPTKDM4ETHRBMEN1KMT2A | |
| SCHEMBL5594708 | 0.75 | MEN1 (1.00) | MAPTKDM4ETHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |