SCHEMBL21579409

SCHEMBL21579409

CC(C)(C)n1cc(C(=O)O)c(N)nc1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GABRP O00591 3/20 0.35
GABRD O14764 3/20 0.35
GABRA1 P14867 3/20 0.35
GABRB1 P18505 3/20 0.35
GABRG2 P18507 3/20 0.35
GABRB3 P28472 3/20 0.35
GABRA5 P31644 3/20 0.35
GABRA3 P34903 3/20 0.35
GABRA2 P47869 3/20 0.35
GABRB2 P47870 3/20 0.35
GABRA4 P48169 3/20 0.35
GABRE P78334 3/20 0.35
GABRA6 Q16445 3/20 0.35
GABRG1 Q8N1C3 3/20 0.35
GABRG3 Q99928 3/20 0.35
GABRQ Q9UN88 3/20 0.35
KDM4E B2RXH2 2/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20792486 0.87 ALDH1A1 (0.42) ALDH1A1LMNAKDM4ERETLCK
SCHEMBL20792663 0.82 ALDH1A1 (0.35) ALDH1A1LMNARET
SCHEMBL19310470 0.77 GABRP (0.38) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL18699041 0.75 NAPRT (0.36) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL23366327 0.74 PI4KA (0.32) ALDH1A1LMNA
SCHEMBL26269524 0.74 TET2 (0.40) ALDH1A1LMNALCKSRC
SCHEMBL12702632 0.74 ALB (0.36) ALDH1A1LMNATOP2ATOP2B
SCHEMBL29189702 0.74 KDM4E (0.36) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL21579408 0.73 ALDH1A1 (0.33) ALDH1A1LMNATBK1
SCHEMBL19310476 0.73 LMNA (0.47) ALDH1A1LMNAGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037636-B2 Polynucleotide synthesis method, kit and system OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-07-16 US disclosed
US-12037636-B2 Polynucleotide synthesis method, kit and system OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2024-07-16 US disclosed
US-20220396818-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-15 US disclosed
US-20220213537-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-07-07 US disclosed
US-20220177938-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2022-06-09 US disclosed
US-20210388432-A1 POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-12-16 US disclosed
US-10927394-B2 Methods and reagents for synthesising polynucleotide molecules OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2021-02-23 US disclosed
US-20190352687-A1 METHODS AND REAGENTS FOR SYNTHESISING POLYNUCLEOTIDE MOLECULES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2019-11-21 US disclosed