Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.67 |
| ▸ | CA2 | P00918 | 17/20 | 0.67 |
| ▸ | CA9 | Q16790 | 17/20 | 0.67 |
| ▸ | CA12 | O43570 | 6/20 | 0.67 |
| ▸ | CA4 | P22748 | 11/20 | 0.66 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703929 | 1.00 | CA1 (0.67) | CA1CA2CA9CA12CA4 | |
| SCHEMBL21580603 | 1.00 | CA1 (0.67) | CA1CA2CA9CA12CA4 | |
| SCHEMBL15177203 | 0.84 | ALDH1A1 (0.54) | CA1CA2CA9CA12MAPT | |
| SCHEMBL14404150 | 0.80 | MEN1 (0.64) | CA1CA2CA9CA12MAPT | |
| SCHEMBL12670669 | 0.78 | MAPT (0.67) | MAPT | |
| SCHEMBL28801368 | 0.77 | CA1 (0.59) | CA1CA2CA9CA12CA4 | |
| SCHEMBL31704024 | 0.76 | CA1 (0.51) | CA1CA2CA9CA12CA4 | |
| SCHEMBL15187708 | 0.76 | RAB9A (0.57) | CA1CA2CA9CA4MAPT | |
| SCHEMBL28874997 | 0.76 | MEN1 (0.57) | MAPT | |
| SCHEMBL31703719 | 0.75 | CA9 (0.55) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3796918-A1 | PROMOTION OF EPITHELIAL REPAIR VIA THE ADMINISTRATION OF ACTIVATORS OF PI3K/AKT SIGNALLING | Telethon Kids Institute (AU) | 2021-03-31 | — | — | EP | claimed |
| WO-2019222801-A1 | PROMOTION OF EPITHELIAL REPAIR VIA THE ADMINISTRATION OF ACTIVATORS OF PI3K/AKT SIGNALLING | TELETHON KIDS INSTITUTE (AU) | 2019-11-28 | — | — | WO | claimed |