Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.55 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26454172 | 0.90 | OPRM1 (0.58) | OPRM1OPRD1 | |
| SCHEMBL21581709 | 0.90 | OPRM1 (0.58) | OPRM1OPRD1 | |
| SCHEMBL21581716 | 0.88 | OPRM1 (0.56) | OPRM1OPRD1 | |
| SCHEMBL17722485 | 0.88 | OPRM1 (0.56) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL17722493 | 0.88 | OPRM1 (0.56) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL26455037 | 0.87 | OPRM1 (0.54) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL26454528 | 0.87 | OPRM1 (0.51) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL21581737 | 0.86 | OPRM1 (0.55) | OPRM1OPRD1 | |
| SCHEMBL21581726 | 0.86 | OPRM1 (0.53) | OPRM1OPRD1BDKRB2 | |
| SCHEMBL29590305 | 0.86 | OPRM1 (0.60) | OPRM1OPRD1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133885-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | THE UNIVERSITY OF SYDNEY (AU) | 2023-05-04 | — | — | US | disclosed |
| WO-2019222805-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | THE UNIVERSITY OF SYDNEY (AU) | 2019-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133885-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | SCLY, SRM, SELENOI | OPRM1 4141/4885OPRD1 4379/4885BDKRB2 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.