SCHEMBL21581883

SCHEMBL21581883

COC[C@H]1O[C@H](OCc2ccccc2)[C@H](NC(C)=O)[C@@H](OC)[C@@H]1F

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 6/20 0.49
▸ SSTR3 P32745 5/20 0.49
▸ SSTR2 P30874 3/20 0.49
▸ SSTR1 P30872 1/20 0.49
▸ SSTR4 P31391 1/20 0.49
▸ POLB P06746 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ LMNA P02545 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ MCHR1 Q99705 9/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23631546 0.91 L3MBTL1 (0.48) POLBL3MBTL1LMNAKMT2A
SCHEMBL5840913 0.86 POLB (0.49) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL5840906 0.86 POLB (0.49) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL23631561 0.84 POLB (0.66) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL13491599 0.83 POLB (0.52) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL7583524 0.83 POLB (0.52) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL23631544 0.82 POLB (0.52) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL23631539 0.81 POLB (0.55) POLBL3MBTL1LMNAKMT2A
SCHEMBL23631545 0.81 POLB (0.55) SSTR5SSTR3SSTR2SSTR1SSTR4
SCHEMBL23631559 0.80 POLB (0.50) SSTR5SSTR3SSTR2SSTR1SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365212-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives UTI LIMITED PARTNERSHIP (CA) 2022-06-21 — — US disclosed
US-20210214384-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES UTI LIMITED PARTNERSHIP (CA) 2021-07-15 — — US disclosed
WO-2019227228-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES UTI LIMITED PARTNERSHIP (CA) 2019-12-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11365212-B2 Fluorinated N-acetyl glucosamine analogs and xylose derivatives FUT6, FUT5, B3GNT2 SSTR5 878/4885SSTR3 833/4885SSTR2 1291/4885
US-20210214384-A1 FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES FUT6, FUT5, B3GNT2 SSTR5 878/4885SSTR3 833/4885SSTR2 1291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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