SCHEMBL2158195

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2150690	0.94	TDP1 (0.46)	TDP1L3MBTL1CYP3A4CYP2C9CYP2C19
	SCHEMBL15946009	0.81	HDAC4 (0.48)	—
	SCHEMBL2202635	0.79	RAB9A (0.45)	TDP1L3MBTL1CYP3A4CYP2C9CYP2C19
	SCHEMBL2157970	0.78	TDP1 (0.46)	TDP1L3MBTL1POLBMAPK1CYP1B1
	SCHEMBL2159068	0.78	TDP1 (0.57)	TDP1L3MBTL1POLBCYP1B1ACHE
	SCHEMBL2150910	0.78	HTR6 (0.43)	TLR8
	SCHEMBL10352124	0.76	TDP1 (0.60)	TDP1L3MBTL1CYP1B1MAOBACHE
	SCHEMBL614087	0.76	TDP1 (0.48)	TDP1L3MBTL1MAPK1CYP1B1MAOB
	SCHEMBL2150855	0.76	TDP1 (0.51)	TDP1L3MBTL1HPGDSMN1; SMN2ACHE
	SCHEMBL15946007	0.75	HDAC4 (0.46)	MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.