Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32671770 | 0.89 | HTT (0.53) | HTTTDP1ESPL1ATMALDH1A1 | |
| SCHEMBL2924231 | 0.89 | HTT (0.53) | HTTTDP1ESPL1ATMALDH1A1 | |
| Sulfuric Acid SCHEMBL29027308 | 0.82 | HTT (0.46) | HTTTDP1ESPL1ALDH1A1VCAM1 | |
| SCHEMBL17670373 | 0.78 | PDK1 (0.42) | TDP1ESPL1ATMALDH1A1HIF1A | |
| SCHEMBL20987168 | 0.78 | MAPT (0.51) | TDP1ESPL1ATMALDH1A1HIF1A | |
| SCHEMBL30459727 | 0.76 | ALDH1A1 (0.41) | TDP1ESPL1ATMALDH1A1HIF1A | |
| SCHEMBL17542594 | 0.76 | TDP1 (0.40) | HTTTDP1ESPL1ATMALDH1A1 | |
| SCHEMBL30613047 | 0.76 | CYP1A2 (0.38) | TDP1ATMALDH1A1HIF1AMAPT | |
| SCHEMBL17683072 | 0.76 | ALDH1A1 (0.41) | TDP1ESPL1ATMALDH1A1HIF1A | |
| SCHEMBL15486393 | 0.76 | HTT (0.49) | HTTTDP1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327402-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN PHARMACY | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2024-10-03 | — | — | US | disclosed |
| WO-2019228330-A1 | SUBSTITUTED BENZO[D]IMIDAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 深圳市塔吉瑞生物医药有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327402-A1 | PYRIMIDINE OR PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN PHARMACY | WEE1, WEE2, EGFR | HTT 4407/4885TDP1 1074/4885ESPL1 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.