SCHEMBL21583539

SCHEMBL21583539

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)oc4cccc(-c6ccccc6)c45)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BACE1 P56817 1/20 0.32
PTGER4 P35408 1/20 0.32
HCRTR1 O43613 1/20 0.32
TP53 P04637 1/20 0.31
HPSE Q9Y251 2/20 0.31
TSPO P30536 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
PIM1 P11309 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258141 0.97 KDM4E (0.37) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL26761378 0.97 ATM (0.35) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21583554 0.96 KDM4E (0.36) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL23814136 0.95 PLA2G2A (0.32) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21583560 0.95 PDE10A (0.34) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21671347 0.95 BACE1 (0.33) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21583559 0.95 KDM4E (0.35) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21583571 0.95 KDM4E (0.35) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL21583542 0.95 KDM4E (0.37) PDE10AKDM4EATML3MBTL1BACE1
SCHEMBL24215898 0.94 KDM4E (0.36) KDM4EATML3MBTL1BACE1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-08-10 US disclosed
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-08-10 US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed
EP-3575296-B1 TRIAZINE COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2021-09-29 EP disclosed
EP-3575296-A1 TRIAZINE COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2019-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 PDE10A 1595/4885KDM4E 3503/4885ATM 4071/4885
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 PDE10A 1595/4885KDM4E 3503/4885ATM 4071/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 PDE10A 3503/4885KDM4E 2556/4885ATM 1838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.