SCHEMBL21583540

SCHEMBL21583540

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5c(-c6ccccc6)cccc54)c3)nc(-c3ccc4c(c3)oc3cccc(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.33
TP53 P04637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 3/20 0.32
PDE10A Q9Y233 1/20 0.31
HCRTR1 O43613 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
MAPK1 P28482 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965004 0.96 KDM4E (0.34) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21964384 0.96 MAPT (0.34) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21583542 0.96 KDM4E (0.37) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21128957 0.95 MAPT (0.33) BACE1TP53KDM4EATML3MBTL1
SCHEMBL16805681 0.95 BACE1 (0.36) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21666806 0.95 PTGER4 (0.34) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21583554 0.95 KDM4E (0.36) BACE1TP53KDM4EATML3MBTL1
SCHEMBL23339339 0.94 BACE1 (0.33) BACE1TP53KDM4EATML3MBTL1
SCHEMBL21129105 0.94 HCRTR1 (0.34) TP53KDM4EATML3MBTL1MAPT
SCHEMBL21583571 0.94 KDM4E (0.35) BACE1TP53KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024144179-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-07-04 WO disclosed
WO-2024144176-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY APPARATUS 삼성에스디아이 주식회사 2024-07-04 WO disclosed
WO-2024128699-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-06-20 WO disclosed
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-26 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-08-10 US disclosed
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-08-10 US disclosed
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 US disclosed
EP-3689867-B1 COMPOSITION, ORGANIC SEMICONDUCTOR LAYER AND ELECTRONIC DEVICE NOVALED GMBH (DE) 2021-12-15 EP disclosed
EP-3575296-B1 TRIAZINE COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2021-09-29 EP disclosed
WO-2020157204-A1 COMPOSITION, ORGANIC SEMICONDUCTOR LAYER AND ELECTRONIC DEVICE NOVALED GMBH (DE) 2020-08-06 WO disclosed
EP-3689867-A1 COMPOSITION, ORGANIC SEMICONDUCTOR LAYER AND ELECTRONIC DEVICE Novaled GmbH (DE) 2020-08-05 EP disclosed
EP-3575296-A1 TRIAZINE COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2019-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255109-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 BACE1 1361/4885TP53 4826/4885KDM4E 3503/4885
US-20230345828-A1 COMPOUND, COMPOSITION AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OXER1, OR51E2 BACE1 1361/4885TP53 4826/4885KDM4E 3503/4885
US-20220393115-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF LEF1, L1CAM, PIEZO1 BACE1 1488/4885TP53 3558/4885KDM4E 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.