Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747423 | 0.83 | TAAR1 (0.65) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL21583868 | 0.83 | TAAR1 (0.65) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL30211131 | 0.83 | TAAR1 (0.65) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL2747426 | 0.83 | TAAR1 (0.65) | TAAR1SLC6A2MAOASLC6A4SLC6A3 | |
| SCHEMBL6173498 | 0.81 | LTA4H (0.41) | SIGMAR1BCHELTA4H | |
| SCHEMBL12707337 | 0.80 | CYP1A2 (0.49) | SLC6A2MAOASLC6A3MAOBBCHE | |
| SCHEMBL4826818 | 0.80 | LTA4H (0.45) | MAOAMAOBLTA4HCYP4F2CYP4A11 | |
| SCHEMBL31160636 | 0.79 | MEN1 (0.59) | SLC6A2MAOASLC6A3MAOBBCHE | |
| SCHEMBL5042093 | 0.79 | ALOX5 (0.55) | SLC6A2MAOASLC6A3MAOBBCHE | |
| SCHEMBL16710629 | 0.79 | MAOB (0.50) | SLC6A2SLC6A3MAOBBCHECYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228443-A1 | SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2019-12-05 | — | — | WO | disclosed |