Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173496 | 0.85 | LTA4H (0.37) | LTA4HBCHESIGMAR1RRM1MEN1 | |
| SCHEMBL16429080 | 0.82 | MEN1 (0.46) | LTA4HBCHESIGMAR1RRM1MEN1 | |
| SCHEMBL21583955 | 0.81 | TAAR1 (0.50) | LTA4HBCHESIGMAR1 | |
| SCHEMBL16429306 | 0.79 | BCHE (0.44) | LTA4HBCHEMEN1RAB9AKMT2A | |
| SCHEMBL4826818 | 0.73 | LTA4H (0.45) | LTA4HMEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5117678 | 0.72 | TRPA1 (0.41) | — | |
| SCHEMBL21583965 | 0.71 | SIGMAR1 (0.49) | BCHESIGMAR1RRM1MEN1KMT2A | |
| SCHEMBL12707337 | 0.71 | CYP1A2 (0.49) | BCHEMEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5042093 | 0.70 | ALOX5 (0.55) | BCHEMEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL31160636 | 0.70 | MEN1 (0.59) | BCHEMEN1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534693-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004022523-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | claimed |