Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584471 | 0.87 | ADORA2A (0.44) | SMN1; SMN2LMNAHPGDTP53ALDH1A1 | |
| SCHEMBL1654721 | 0.82 | CYP1A2 (0.43) | SMN1; SMN2LMNAHPGDALDH1A1MAPT | |
| SCHEMBL21584422 | 0.79 | ROCK2 (0.41) | SMN1; SMN2TP53ALDH1A1MAPTROCK2 | |
| SCHEMBL21584377 | 0.77 | GAA (0.38) | SMN1; SMN2LMNAALDH1A1KMT2AGAA | |
| SCHEMBL21584415 | 0.76 | MEP1B (0.35) | SMN1; SMN2LMNAHPGDTP53ALDH1A1 | |
| SCHEMBL21584461 | 0.75 | KDM4E (0.40) | SMN1; SMN2LMNAHPGDALDH1A1MAPT | |
| SCHEMBL25273221 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTROCK2ROCK1 | |
| SCHEMBL21584408 | 0.74 | LMNA (0.43) | SMN1; SMN2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL21584389 | 0.74 | CYP1A2 (0.36) | ALDH1A1MAPTKMT2AGAAPOLB | |
| SCHEMBL28929271 | 0.74 | EGLN1 (0.36) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227771-A1 | SUBSTITUTED PYRIMIDINE-4-FORMIC ACID DERIVATIVE, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |