SCHEMBL2158447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2248230	0.91	IKBKB (0.61)	NPSR1KDM4ERXFP1ALDH1A1HPGD
	SCHEMBL2158564	0.91	ALDH1A1 (0.53)	NPSR1KDM4ERXFP1ALDH1A1HPGD
	SCHEMBL2157980	0.91	NPSR1 (0.61)	NPSR1KDM4ERXFP1MEN1KMT2A
	SCHEMBL6426603	0.89	NPSR1 (0.60)	NPSR1KDM4ERXFP1
	SCHEMBL2157593	0.89	PTPN1 (0.56)	NPSR1KDM4ERXFP1ALDH1A1HPGD
	SCHEMBL2157863	0.89	NPSR1 (0.54)	NPSR1KDM4ERXFP1ALDH1A1HPGD
	SCHEMBL2158562	0.89	NPSR1 (0.54)	NPSR1KDM4ERXFP1ALDH1A1HPGD
	SCHEMBL2158465	0.89	ACLY (0.60)	NPSR1KDM4ERXFP1
	SCHEMBL2158092	0.89	NPSR1 (0.55)	NPSR1KDM4ERXFP1
	SCHEMBL2157871	0.89	NPSR1 (0.58)	NPSR1KDM4ERXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.