Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851905 | 0.70 | — | — | |
| SCHEMBL13460109 | 0.69 | GRIN1 (0.40) | GRIN1GRIN2ABRD4BRD2 | |
| SCHEMBL26456980 | 0.67 | GRIN1 (0.42) | GRIN1GRIN2ABRD4BRD2 | |
| SCHEMBL12228048 | 0.65 | CRBN (0.35) | GRIN1GRIN2ABRD4BRD2 | |
| SCHEMBL34471648 | 0.65 | OPRM1 (0.47) | — | |
| SCHEMBL25738952 | 0.64 | GRIN1 (0.40) | GRIN1GRIN2ABRD4BRD2 | |
| SCHEMBL25837389 | 0.64 | GRIN1 (0.40) | GRIN1GRIN2ABRD4BRD2 | |
| SCHEMBL21584992 | 0.63 | CSF1R (0.34) | GRIN1GRIN2ACSF1R | |
| SCHEMBL761689 | 0.63 | — | — | |
| SCHEMBL16498173 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228252-A1 | HIGHLY ACTIVE CSF1R INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 (CN) | 2019-12-05 | — | — | WO | disclosed |