Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.38 |
| ▸ | SRC | P12931 | 6/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585736 | 0.90 | PDE10A (0.39) | PDE10A | |
| SCHEMBL19813873 | 0.85 | ABL1 (0.44) | ABL1PDE10APIK3C3CDK7CDK9 | |
| SCHEMBL22282976 | 0.73 | EED (0.33) | ABL1PDE10A | |
| SCHEMBL21585742 | 0.72 | SLC6A3 (0.36) | FGFR1SRCABL1EGFRFGFR2 | |
| SCHEMBL21314823 | 0.71 | L3MBTL1 (0.37) | PDE10APIK3C3 | |
| SCHEMBL21808416 | 0.69 | SLC6A3 (0.41) | FGFR1ABL1EGFRBACE1BACE2 | |
| SCHEMBL27945167 | 0.69 | PDE10A (0.37) | PDE10ACDK7CDK9 | |
| SCHEMBL19302651 | 0.69 | PDE10A (0.39) | PDE10APIK3C3 | |
| SCHEMBL25300572 | 0.67 | POLQ (0.40) | FGFR1ABL1EGFRBACE1BACE2 | |
| SCHEMBL19813831 | 0.67 | ABL1 (0.37) | ABL1CDK7CDK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390589-B2 | Herbicidally active substituted phenylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 2022-07-19 | — | — | US | disclosed |
| US-20210317089-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| EP-3802516-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINES | Bayer Aktiengesellschaft (DE) | 2021-04-14 | — | — | EP | disclosed |
| CN-112513028-A | Substituted phenylpyrimidines with herbicidal activity | 拜耳公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2019233862-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317089-A1 | HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINES | DDT, DPYD, GSTP1 | FGFR1 1056/4885SRC 3704/4885ABL1 942/4885 |
| US-11390589-B2 | Herbicidally active substituted phenylpyrimidines | DDT, DPYD, GSTP1 | FGFR1 1056/4885SRC 3704/4885ABL1 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.