Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 4/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.32 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813873 | 0.82 | ABL1 (0.44) | L3MBTL1HSD11B1MAPTABL1KMT2A | |
| SCHEMBL30289567 | 0.77 | PDE10A (0.36) | IGF1RPDE10AHDAC9 | |
| SCHEMBL17841500 | 0.77 | PDE10A (0.36) | IGF1RPDE10AHDAC9 | |
| SCHEMBL19813846 | 0.73 | TSHR (0.39) | GABRG2GABRB3GABRA5MAPK1SMN1; SMN2 | |
| SCHEMBL21585740 | 0.73 | FGFR1 (0.38) | ABL1PDE10A | |
| SCHEMBL19813802 | 0.73 | HPGDS (0.36) | GABRG2GABRB3GABRA5MAPK1HDAC4 | |
| SCHEMBL22282974 | 0.72 | CYP1A2 (0.38) | RAB9AMAPK1SMN1; SMN2NPC1TP53 | |
| SCHEMBL22282975 | 0.72 | HSD11B1 (0.36) | RAB9AMAPK1SMN1; SMN2NPC1TP53 | |
| SCHEMBL19302651 | 0.69 | PDE10A (0.39) | NFKB1NFKB2RELAKDM4EPDE10A | |
| SCHEMBL21585736 | 0.68 | PDE10A (0.39) | EEDSUZ12EZH2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490985-B1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2020-08-05 | — | — | EP | claimed |
| CN-109476647-A | The pyrimidine compound of weeding | 巴斯夫欧洲公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109476647-A | The pyrimidine compound of weeding | 巴斯夫欧洲公司 | 2019-03-15 | — | — | CN | disclosed |