Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17238205 | 0.80 | HDAC4 (0.48) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL22462327 | 0.78 | HDAC4 (0.49) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL17238204 | 0.76 | HDAC4 (0.43) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL21585753 | 0.74 | HDAC4 (0.42) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL4262832 | 0.73 | TSHR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30960327 | 0.73 | TSHR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17238203 | 0.72 | HDAC4 (0.46) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL21585755 | 0.72 | HDAC3 (0.40) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL540542 | 0.72 | TSHR (0.52) | HDAC4HDAC6HDAC3HDAC1CA12 | |
| SCHEMBL1998616 | 0.72 | CES2 (0.60) | HDAC4HDAC6HDAC3HDAC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116956-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-11 | — | — | US | disclosed |
| US-11897904-B2 | Herbicidally active bicyclic benzamides | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-13 | — | — | US | disclosed |
| EP-3713417-B1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | BAYER AG (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-20210323950-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZOYLPYRAZOLES | BAYER AG (DE) | 2021-10-21 | — | — | US | disclosed |
| EP-3802521-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZOYLPYRAZOLES | Bayer Aktiengesellschaft (DE) | 2021-04-14 | — | — | EP | disclosed |
| CN-112513033-A | Herbicidally active bicyclic benzoylpyrazoles | 拜耳公司 | 2021-03-16 | — | — | CN | disclosed |
| US-20200325159-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-15 | — | — | US | disclosed |
| CN-111356368-A | Herbicidally active bicyclic benzamides | 拜耳公司 | 2020-06-30 | — | — | CN | disclosed |
| WO-2019233863-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZOYLPYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897904-B2 | Herbicidally active bicyclic benzamides | CBR3, CBR1, AOX1 | HDAC4 986/4885HDAC6 773/4885HDAC3 204/4885 |
| US-20200325159-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | CBR3, CBR1, AOX1 | HDAC4 986/4885HDAC6 773/4885HDAC3 204/4885 |
| US-20210323950-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZOYLPYRAZOLES | CBR3, CBR1, RTN3 | HDAC4 785/4885HDAC6 1130/4885HDAC3 160/4885 |
| US-20240116956-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | CBR3, CBR1, AOX1 | HDAC4 986/4885HDAC6 773/4885HDAC3 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.