Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22231488 | 0.83 | HPGD (0.58) | ALDH1A1L3MBTL1HPGDHDAC1KDM4E | |
| SCHEMBL18007647 | 0.80 | ALDH1A1 (0.62) | POLBALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL20900686 | 0.78 | ERCC1 (0.57) | POLBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL21586473 | 0.78 | ALDH1A1 (0.40) | POLBMTNR1AMTNR1BALDH1A1L3MBTL1 | |
| SCHEMBL3487707 | 0.75 | MTNR1A (0.45) | POLBMTNR1AMTNR1BALDH1A1TAAR1 | |
| SCHEMBL18232229 | 0.75 | MTNR1A (0.40) | POLBMTNR1AMTNR1BTRPV1ERCC1 | |
| SCHEMBL8532525 | 0.74 | CYP1A2 (0.51) | ALDH1A1L3MBTL1HDAC1KDM4EHDAC2 | |
| SCHEMBL28999845 | 0.73 | KMT2A (0.58) | POLBALDH1A1HPGDHDAC1LMNA | |
| SCHEMBL13080230 | 0.71 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KDM4ELMNAMEN1 | |
| SCHEMBL1501816 | 0.70 | CYP4F2 (0.50) | POLBALDH1A1LMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578547-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University of Queensland (AU) | 2019-12-11 | — | — | EP | disclosed |