Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24281941 | 0.83 | SLC9A1 (0.31) | SLC9A1 | |
| SCHEMBL21449941 | 0.80 | AR (0.34) | SLC6A4 | |
| SCHEMBL21586991 | 0.77 | SLC6A2 (0.30) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL21586870 | 0.76 | CYP2D6 (0.40) | SLC6A4SLC6A3SLC6A2CYP2D6KCNH2 | |
| SCHEMBL25166311 | 0.75 | SLC9A1 (0.38) | TSHRTRPM5SLC9A1 | |
| SCHEMBL7976045 | 0.73 | HTR2A (0.41) | CYP2D6MEN1ALDH1A1MAPTHTT | |
| SCHEMBL7976044 | 0.73 | HTR2A (0.41) | CYP2D6MEN1ALDH1A1MAPTHTT | |
| SCHEMBL7976048 | 0.73 | HTR2A (0.41) | CYP2D6MEN1ALDH1A1MAPTHTT | |
| SCHEMBL19442291 | 0.73 | MEN1 (0.43) | SLC6A4SLC6A3SLC6A2CYP2D6KCNH2 | |
| SCHEMBL20845981 | 0.73 | MEN1 (0.43) | SLC6A4SLC6A3SLC6A2CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578541-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITION, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2019-12-11 | — | — | EP | disclosed |