SCHEMBL25166311

SCHEMBL25166311

OCC1C(c2cc(Cl)cc(Cl)c2)C1(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 6/20 0.38
TRPM4 Q8TD43 1/20 0.33
TRPM5 Q9NZQ8 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976045 0.78 HTR2A (0.41) SLC9A1TRPM4TRPM5
SCHEMBL7976044 0.78 HTR2A (0.41) SLC9A1TRPM4TRPM5
SCHEMBL7976048 0.78 HTR2A (0.41) SLC9A1TRPM4TRPM5
SCHEMBL21587433 0.75 SLC6A4 (0.36) SLC9A1TRPM5TSHR
SCHEMBL18154019 0.70 SLC9A1 (0.42) SLC9A1TSHR
SCHEMBL18160468 0.69 MEN1 (0.30)
SCHEMBL21449941 0.69 AR (0.34)
SCHEMBL21586991 0.69 SLC6A2 (0.30)
SCHEMBL21587435 0.67 SLC9A1 (0.47) SLC9A1TSHR
SCHEMBL18147577 0.67 SLC9A1 (0.47) SLC9A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD SLC9A1 3136/4885TRPM4 546/4885TRPM5 523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.