Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752027 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL21589351 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL11721290 | 0.81 | CA2 (0.71) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL11715144 | 0.81 | CA1 (0.43) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL10064653 | 0.81 | CA2 (0.49) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL15442497 | 0.80 | METAP2 (0.47) | ALDH1A1CA1CA2CA9KDM4E | |
| SCHEMBL5193607 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL5009133 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL12224768 | 0.77 | POLB (0.45) | ALDH1A1HSD17B10CA1CA2CA9 | |
| SCHEMBL11717245 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581617-A1 | COMPOSITIONS COMPRISING A FILM-FORMING POLYMER AND AN AROMATIC ACID OR SALT THEREOF, AND PREPARATION AND USES THEREOF | Synthomer (UK) Ltd. (GB) | 2019-12-18 | — | — | EP | disclosed |