SCHEMBL2158946

SCHEMBL2158946

CC(C)c1[c]cc(-c2ccccc2)c(C(C)C)c1-c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.33
GCGR P47871 1/20 0.33
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718190 0.86 GCGR (0.34) GCGRCDC25ACDC25BPDE4APDE4B
SCHEMBL16150176 0.75 GCGR (0.34) GCGRCDC25ACDC25BPDE4APDE4B
SCHEMBL9933563 0.71 CDC25A (0.33) CDC25ACDC25B
SCHEMBL30731374 0.70 LMNA (0.43) GCGRCDC25ACDC25BPDE4APDE4B
SCHEMBL11313436 0.69 USP7 (0.35) USP7GCGRCDC25ACDC25B
SCHEMBL6838848 0.68 CDC25A (0.41) CDC25ACDC25B
SCHEMBL7712240 0.68 LMNA (0.42) GCGRCDC25ACDC25BPDE4APDE4B
SCHEMBL11326462 0.68 HSP90AA1 (0.39) USP7GCGRCDC25ACDC25BPDE4A
SCHEMBL2160199 0.67 CDC25A (0.38) CDC25ACDC25B
SCHEMBL28423706 0.66 CDC25A (0.44) CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2436714-B1 Distortional composite matrix BOEING CO (US) 2021-01-13 EP disclosed
EP-3068823-B1 FIBER-REINFORCED RESIN COMPOSITES AND METHODS OF MAKING THE SAME BOEING CO (US) 2019-07-24 EP disclosed
EP-3068823-A2 FIBER-REINFORCED RESIN COMPOSITES AND METHODS OF MAKING THE SAME The Boeing Company (US) 2016-09-21 EP disclosed
US-9012533-B2 Fiber-reinforced resin composites and methods of making the same THE BOEING COMPANY (US) 2015-04-21 US disclosed
US-20150080494-A1 Fiber-Reinforced Resin Composites and Methods of Making the Same THE BOEING COMPANY (US) 2015-03-19 US disclosed
US-7985808-B2 Distortional matrix of epoxy resin and diamine THE BOEING COMPANY (US) 2011-07-26 US disclosed
US-20100204416-A1 DISTORTIONAL COMPOSITE MATRIX THE BOEING COMPANY (US) 2010-08-12 US disclosed
US-7745549-B2 Distortional matrix of epoxy resin and diamine THE BOEING COMPANY (US) 2010-06-29 US disclosed
EP-2099844-A1 DISTORTIONAL COMPOSITE MATRIX The Boeing Company (US) 2009-09-16 EP disclosed
WO-2008079592-A1 DISTORTIONAL COMPOSITE MATRIX THE BOEING COMPANY (US) 2008-07-03 WO disclosed
US-20070149725-A1 DISTORTIONAL COMPOSITE MATRIX THE BOEING COMPANY (US) 2007-06-28 US disclosed