Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158946 | 0.86 | USP7 (0.33) | GCGRCDC25ACDC25BPDE4BPDE4A | |
| SCHEMBL16150176 | 0.78 | GCGR (0.34) | GCGRCDC25ACDC25BPDE4BPDE4A | |
| SCHEMBL12816030 | 0.75 | CYP2A6 (0.36) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL770088 | 0.72 | LMNA (0.36) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL22129263 | 0.70 | PTGS1 (0.35) | GCGRPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8480921 | 0.69 | PDCD1 (0.36) | PDE4BPDE4APDE4CPDE4DLMNA | |
| SCHEMBL2160199 | 0.69 | CDC25A (0.38) | CDC25ACDC25BMAPTHTTMETAP2 | |
| SCHEMBL28926448 | 0.68 | BACE1 (0.39) | CDC25ACDC25BLMNAMAPTMETAP2 | |
| SCHEMBL11326822 | 0.67 | GCGR (0.37) | GCGRCDC25ACDC25BPDE4BPDE4A | |
| SCHEMBL9933563 | 0.67 | CDC25A (0.33) | CDC25ACDC25BMETAP2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473915-A1 | Improved barrier PVC resins, compounds and articles derived therefrom | THE B.F. GOODRICH COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |