SCHEMBL2160199

SCHEMBL2160199

CC(C)c1[c]cccc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 1/20 0.35
PTGS2 P35354 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
DPP4 P27487 1/20 0.32
BACE1 P56817 1/20 0.32
METAP2 P50579 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4905489 0.85 MAPT (0.39) HPGDCA12CA1CA2CA9
SCHEMBL8212159 0.83 PTPRC (0.35) CDC25ACDC25BALDH1A1HPGDMAPK1
SCHEMBL10833643 0.78 SIGMAR1 (0.33) MAPT
SCHEMBL16150176 0.77 GCGR (0.34) CDC25ACDC25BBACE1METAP2ADORA3
SCHEMBL9933563 0.77 CDC25A (0.33) CDC25ACDC25BBACE1METAP2ADORA3
SCHEMBL9381068 0.74 APP (0.42) ALDH1A1HSD17B10HPGDMETAP2CA12
SCHEMBL11762666 0.74 ALDH1A1 (0.34) ALDH1A1CA2
SCHEMBL3915759 0.73
SCHEMBL11032010 0.73 MAPT (0.40) CDC25ACDC25BHPGDCYP2A6PTGS2
SCHEMBL695988 0.72 PDCD1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774273-A ELECTRICAL SUPPLIES, HOUSINGS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-27 US claimed
EP-2436714-B1 Distortional composite matrix BOEING CO (US) 2021-01-13 EP disclosed
CN-105980476-B Fiber-reinforced resin composite and method for producing same 波音公司 2019-12-10 CN disclosed
EP-3068823-B1 FIBER-REINFORCED RESIN COMPOSITES AND METHODS OF MAKING THE SAME BOEING CO (US) 2019-07-24 EP disclosed
EP-3068823-A2 FIBER-REINFORCED RESIN COMPOSITES AND METHODS OF MAKING THE SAME The Boeing Company (US) 2016-09-21 EP disclosed
US-9012533-B2 Fiber-reinforced resin composites and methods of making the same THE BOEING COMPANY (US) 2015-04-21 US disclosed
US-20150080494-A1 Fiber-Reinforced Resin Composites and Methods of Making the Same THE BOEING COMPANY (US) 2015-03-19 US disclosed
US-7985808-B2 Distortional matrix of epoxy resin and diamine THE BOEING COMPANY (US) 2011-07-26 US disclosed
US-20100204416-A1 DISTORTIONAL COMPOSITE MATRIX THE BOEING COMPANY (US) 2010-08-12 US disclosed
US-7745549-B2 Distortional matrix of epoxy resin and diamine THE BOEING COMPANY (US) 2010-06-29 US disclosed
US-5840722-A ADMINISTERING TO INHIBIT ENDOTHELIN RECEPTORS BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
US-5661106-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-08-26 US disclosed
US-5097056-A Reaction with phenol or mixture of phenols, continuously removing water and distillation BROMINE COMPOUNDS LTD. (IL) 1992-03-17 US disclosed
US-4774273-A ELECTRICAL SUPPLIES, HOUSINGS BAYER AKTIENGESELLSCHAFT (DE) 1988-09-27 US disclosed
EP-0170851-B1 ARYL ESTER OF PERFLUOROALKANE-SULPHONIC ACID AS AN ANTIDRIPPING AGENT IN FLAME-RESISTANT COMPOSITIONS BASED ON THERMOPLASTIC AROMATIC POLYCARBONATES BAYER AG (DE) 1987-09-09 EP disclosed
EP-0170851-A1 Aryl ester of perfluoroalkane-sulphonic acid as an antidripping agent in flame-resistant compositions based on thermoplastic aromatic polycarbonates BAYER AG (DE) 1986-02-12 EP disclosed
WO-1981002021-A1 STABILIZATION OF POLYPHENYLENE ETHER-COMPOSITIONS BY TETRASUBSTITUTED PIPERIDINES GEN ELECTRIC (US) 1981-07-23 WO disclosed
US-4202843-A Process for the production of organic phosphates by nitric acid oxidation of organic phosphites TENNECO CHEMICALS, INC. (US) 1980-05-13 US disclosed
US-4042586-A ADRENERGIC BLOCKING AGENTS MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1977-08-16 US disclosed
US-3946009-A ADRENERGIC BLOCKING AGENTS MERCK SHARP & DOHME (I.A.) CORPORATION (US) 1976-03-23 US disclosed